Preventive healthcare · Diagnostics · Cardiovascular · India
India has got very good at making tests cheap. We have not got any better at knowing what to ask of them.
Farhat Ali Khan5 min read

A standard Indian full body check-up contains the tests it contains for reasons that have nothing to do with you. Those tests are cheap to run in bulk, the lab already owns the machines, each produces a printable number, and together they hit a price a company will pay by headcount. The package was built around what is easy to produce, then sold as though it answers a question. Cochrane, updating its review of general health checks in adults in 2019, found they did not reduce deaths overall, or from heart disease, or from cancer. What they reliably increased was the number of new diagnoses. Italy did the opposite: it picked one group, asked one question, and chose the single test that answers it. Sudden cardiac death among screened athletes fell 89% over 26 years. The difference is the order of operations, not the volume of testing.
More than 4,500 people ran the Nandi Hills Monsoon Marathon on Sunday, 9th Aug. One of the runners in the 21k was 31, originally from Punjab, living in Bengaluru and working at a company in Manyata Tech Park. Yes he was just like many of us in the corporate hustle trying to find an escape in now what is becoming an increasing popular hobby. He collapsed on the uphill stretch past the halfway mark and was taken to the hospital at Muddenahalli, where he died of suspected cardiac arrest.
The first reaction from most people was that he was fit. He probably was, by the way we normally use the word. Fit for us usually means you can cover the distance, or your weight and body fat are where you want them, or your last health check came back normal. But, What does a health check actually tell you?
Almost everyone reading this has had one. And almost everyone took away the same single piece of information from it, which is that the report said normal.
Think about what is inside a standard full body check-up in India. Fasting sugar or HbA1c, which is your average blood sugar over the last three months. A lipid panel for cholesterol. Liver and kidney function, thyroid, a blood count, urine routine, and a chest X ray or an ultrasound if you paid for the higher tier. Some packages add a resting ECG, taken while you are lying still on a bed. The list barely changes whether you buy it from a diagnostic chain, get it through your employer, or walk into a hospital.
Now ask why those particular tests and not others. It is not because someone sat down and worked out what a specific person needs to know. It is because those tests are cheap to run in bulk, the lab already owns the machines, they can all be processed overnight, each one produces a number you can print, and together they land on a price that people will pay. Companies buy these packages by headcount, so the contents are chosen to fit a per employee budget.
In other words, the package was built around what is easy to produce, and then sold as though it answers a question.
This is the same gap I wrote about last week with general hospitals. One institution trying to be everything to everyone, mixing very different kinds of work under one roof, until nobody can tell what value is actually being created. The check-up is a smaller version of the same thing. One product, sold to a 31 year old who is about to run 21 kilometres uphill and to a 55 year old who has not walked much for a long time, and both of them get the same set of tests.
This is not just my opinion.
Cochrane is a global network of researchers that does one specific job. Instead of running new studies, they collect every decent study that has already been done on a question, remove badly designed ones, and pool the rest to see what the whole body of evidence says together. One trial can get a fluke result. It is much harder for twenty of them to be wrong in the same direction. That is why doctors and health ministries treat a Cochrane review as close to a settled answer. Cochrane also does not take money from companies that sell the treatments it reviews, so there is nobody standing behind the conclusion with something to sell.
Cochrane looked at general health checks in adults and updated the review in 2019. They found that "these check-ups did not reduce deaths overall, or deaths from heart disease, or deaths from cancer." What they did reliably increase was the number of new diagnoses. More findings, no change in outcomes. Each extra finding then leads to a follow up test, a specialist visit, and a bit of worry the person now carries around. When families are already paying close to 40% of health spending from their own savings, that is not a harmless outcome.
None of this means testing does not work. A test ordered to answer something specific is one of the most useful things in medicine. A test ordered because it came in the package is just a number waiting for someone to worry about it.
So what does first type look like when a whole country does it?
Italy is the one place that has run this properly and for long enough to know what happened. After a series of young athletes died during sport in the 1970s, Italy passed a law making a medical check compulsory before anyone could compete, and from 1982 that check has included a 12 lead ECG. Twelve lead means electrodes across the chest and limbs recording the heart's electrical activity from twelve angles, which is the full version rather than the short strip that comes in a check-up package. Every competitive athlete in the country, every year, for the last four decades.
Also, what Italy did not do. It did not add more tests to the general population. It picked one group, asked one question about that group, and chose the one test that answers it. The question was whether this person has a heart condition that hard exercise could turn fatal.
Then they did the part that makes this useful. They tracked the Veneto region for 26 years to see whether it had worked. Sudden cardiac death among screened athletes fell by 89%, from 3.6 down to 0.4 for every 100,000 athletes followed for a year. Over the same period, the rate among people of the same age who were not athletes and were not screened barely moved, which matters because it rules out the easy explanation that Italians were simply getting healthier. Most of the drop came from fewer deaths caused by cardiomyopathy, meaning a disease of the heart muscle itself, usually muscle that has grown thicker than it should be. And over those same years, more athletes were being identified with exactly that condition at screening. The thing they were looking for is the thing they found, and the thing that stopped killing people. That is what a test tied to a question looks like.
Now the part that usually gets left out. About 2% of screened athletes were told they could not compete. For a small number that was a life saved. For others it was a sport taken away on the basis of a finding that might never have harmed them, and at the moment there is no way to know which is which from the outside.
There is also a real argument about how much the Italian numbers prove. Italy watched what happened after a law was passed. It did not split similar athletes into a screened group and an unscreened one, so you cannot completely rule out that something else changed over 26 years. A Belgian health authority reviewed the evidence and concluded it does not support requiring an ECG for every athlete. The United States goes the other way entirely and screens on medical history and a physical examination, no routine ECG at all. This is a live disagreement between people who have spent careers on it.
Which is fine, because none of that is the point I am making. Whether India should require ECGs before races is a question for cardiologists and race organisers. The point is the order of operations. Italy started with a question and then chose a test. We buy a set of tests and hope a question turns up to fit them.
The useful question is not whether you are healthy. It is what you are about to ask your body to do, and whether anything in your history changes the answer.
A hill race in the monsoon is not the same event as the flat runs most people train on. The climb keeps the demand high through the whole second half, the humidity limits how well you cool down, and your heart rate keeps creeping up even when your pace does not. A lot of people move up to the 21k simply because they finished the 10k last year, and on a climb that is a bigger jump than the distance suggests.
Three things actually change what you should do next.
Any of those turns a general worry into a specific question, and a specific question is the only kind a cardiologist can do much with. If none of them apply to you, then honestly, another round of the usual tests will not tell you anything you can act on.
There is a part of this that has nothing to do with testing.
When someone's heart stops during a race, what happens in the first few minutes decides the outcome. Chest compressions started immediately, and a defibrillator close enough to reach. Not the ambulance, and not the hospital. On a course stretched thin along a hill, the person nearest to them is another runner. In a field of 4,500, very few would know what to do.
This is the same idea as putting the right care in the right place, applied to the emergency end of it. Defibrillators along the route instead of only at the start and finish. Marshals who have been trained to use them. A response plan that runners can see before they register. The big city marathons mostly do this now. The regional and destination runs, which is where most of the growth is happening, often do not.
The check-up is not going to fix itself, because the reasons it exists in this shape have not changed. Labs sell packages, companies buy them by headcount, and a report that says normal is a satisfying thing to hand someone. But any of us can step out of the package by starting with a question instead of a price list. That part costs nothing.
It means the tests in that particular package came back inside their reference ranges. Those tests were selected for what is cheap to run in bulk and fits a per employee budget, not for what any individual needs to know, so a normal report answers a question nobody specifically asked about you.
Cochrane updated its review of general health checks in adults in 2019 and found they did not reduce deaths overall, or deaths from heart disease, or deaths from cancer. What they reliably increased was the number of new diagnoses, each of which leads to follow-up tests, specialist visits and worry.
That is a live disagreement. Italy has required a 12 lead ECG for competitive athletes since 1982 and sudden cardiac death among screened athletes fell 89% over 26 years in Veneto. A Belgian authority reviewed the same evidence and concluded it does not support universal athlete ECG, and the United States screens on history and physical examination with no routine ECG.
Three things turn a general worry into a specific question a cardiologist can work with: whether anyone in your family died suddenly and young and whether the cause was confirmed, whether you have ever blacked out or come close during hard effort rather than after finishing, and whether your chest feels tight or heavy at an effort that used to feel easy.
Written by Farhat Ali Khan, Co-founder, Peak Brain.
Published . Last updated .
Originally published on LinkedIn.
General health information, not medical advice, diagnosis or treatment. If you think you may have a medical emergency, call your local emergency number.
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